Variants of PEAR1 Are Associated With Outcome in Patients With ACS and Stable CAD Undergoing PCI

by Fabian Stimpfle, Maike Bauer, Dominik Rath, Elke Schaeffeler, Elke Schaeffeler, Matthias Schwab, Matthias Schwab, Matthias Schwab, Matthias Schwab, Meinrad Gawaz, Stefan Winter, Stefan Winter, Tobias Geisler
Published 2018-05-01

Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs).

by Anne T Nies, Ute Hofmann, Claudia Resch, Elke Schaeffeler, Maria Rius, Matthias Schwab
Published 2011-01-01

The Membrane Transporter OAT7 (SLC22A9) Is Not a Susceptibility Factor for Osteoporosis in Europeans

by Anne T. Nies, Anne T. Nies, Stefan Weiss, Stefan Weiss, Elke Schaeffeler, Elke Schaeffeler, Anke Hannemann, Anke Hannemann, Uwe Völker, Uwe Völker, Henri Wallaschofski, Matthias Schwab, Matthias Schwab, Matthias Schwab
Published 2020-08-01

Impact of Vitamin D Receptor VDR rs2228570 Polymorphism in Oldest Old

by Melanie Glocke, Florian Lang, Elke Schaeffeler, Thomas Lang, Matthias Schwab, Undine E. Lang
Published 2013-09-01

Impact of p38 MAP Kinase Inhibitors on LPS-Induced Release of TNF-α in Whole Blood and Primary Cells from Different Species

by Sarah Fehr, Anke Unger, Elke Schaeffeler, Sonja Herrmann, Stefan Laufer, Matthias Schwab, Wofgang Albrecht
Published 2015-07-01

GPla Polymorphisms Are Associated with Outcomes in Patients at High Cardiovascular Risk

by Dominik Rath, Elke Schaeffeler, Elke Schaeffeler, Stefan Winter, Stefan Winter, Semjon Levertov, Karin Müller, Michal Droppa, Fabian Stimpfle, Harald F. Langer, Meinrad Gawaz, Matthias Schwab, Matthias Schwab, Matthias Schwab, Matthias Schwab, Tobias Geisler
Published 2017-08-01

Influence of NOD2 Variants on Trichuris suis ova Treatment Outcome in Crohn’s Disease

by Simon U. Jaeger, Simon U. Jaeger, Elke Schaeffeler, Elke Schaeffeler, Stefan Winter, Stefan Winter, Roman Tremmel, Roman Tremmel, Jürgen Schölmerich, Nisar Malek, Eduard F. Stange, Matthias Schwab, Matthias Schwab, Matthias Schwab, Matthias Schwab, Jan Wehkamp
Published 2018-07-01

The Impact of CYP3A4*22 on Tacrolimus Pharmacokinetics and Outcome in Clinical Practice at a Single Kidney Transplant Center

by Emaad Abdel-Kahaar, Emaad Abdel-Kahaar, Stefan Winter, Stefan Winter, Roman Tremmel, Roman Tremmel, Elke Schaeffeler, Elke Schaeffeler, Christoph J. Olbricht, Eberhard Wieland, Matthias Schwab, Matthias Schwab, Maria Shipkova, Simon U. Jaeger, Simon U. Jaeger
Published 2019-09-01

Clinical Trial: CYP2D6 Related Dose Escalation of Tamoxifen in Breast Cancer Patients With Iranian Ethnic Background Resulted in Increased Concentrations of Tamoxifen and Its Metab...

by Zahra Khalaj, Zohreh Baratieh, Parvaneh Nikpour, Parvaneh Nikpour, Matthias Schwab, Matthias Schwab, Matthias Schwab, Elke Schaeffeler, Elke Schaeffeler, Fariborz Mokarian, Hossein Khanahmad, Rasoul Salehi, Rasoul Salehi, Thomas E. Mürdter, Thomas E. Mürdter, Mansoor Salehi, Mansoor Salehi, Mansoor Salehi
Published 2019-05-01

Identification of Cardiomyopathy-Associated Circulating miRNA Biomarkers in Muscular Dystrophy Female Carriers Using a Complementary Cardiac Imaging and Plasma Profiling Approach

by Anca Florian, Alexandru Patrascu, Roman Tremmel, Sabine Rösch, Udo Sechtem, Matthias Schwab, Matthias Schwab, Matthias Schwab, Elke Schaeffeler, Ali Yilmaz
Published 2018-12-01

SDF1 Polymorphisms Influence Outcome in Patients with Symptomatic Cardiovascular Disease.

by Dominik Rath, Elke Schaeffeler, Stefan Winter, Jens Hewer, Karin Müller, Michal Droppa, Fabian Stimpfle, Meinrad Gawaz, Matthias Schwab, Tobias Geisler
Published 2016-01-01

A variant of the SLC10A2 gene encoding the apical sodium-dependent bile acid transporter is a risk factor for gallstone disease.

by Olga Renner, Simone Harsch, Elke Schaeffeler, Stefan Winter, Matthias Schwab, Marcin Krawczyk, Jonas Rosendahl, Henning Wittenburg, Frank Lammert, Eduard F Stange
Published 2009-10-01

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort

by Kathrin Klein, Kathrin Klein, Roman Tremmel, Roman Tremmel, Stefan Winter, Stefan Winter, Sarah Fehr, Sarah Fehr, Florian Battke, Florian Battke, Tim Scheurenbrand, Tim Scheurenbrand, Elke Schaeffeler, Elke Schaeffeler, Saskia Biskup, Saskia Biskup, Matthias Schwab, Matthias Schwab, Matthias Schwab, Matthias Schwab, Ulrich M. Zanger, Ulrich M. Zanger
Published 2019-01-01

Clinical utility of the S3-score for molecular prediction of outcome in non-metastatic and metastatic clear cell renal cell carcinoma

by Florian Büttner, Stefan Winter, Steffen Rausch, Jörg Hennenlotter, Stephan Kruck, Arnulf Stenzl, Marcus Scharpf, Falko Fend, Abbas Agaimy, Arndt Hartmann, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Published 2018-07-01

α2-Adrenergic Receptor in Liver Fibrosis: Implications for the Adrenoblocker Mesedin

by Ute A. Schwinghammer, Magda M. Melkonyan, Lilit Hunanyan, Roman Tremmel, Ralf Weiskirchen, Erawan Borkham-Kamphorst, Elke Schaeffeler, Torgom Seferyan, Wolfgang Mikulits, Konstantin Yenkoyan, Matthias Schwab, Lusine Danielyan
Published 2020-02-01

Data‐driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment

by Rebekka Fendt, Ute Hofmann, Annika R. P. Schneider, Elke Schaeffeler, Rolf Burghaus, Ali Yilmaz, Lars Mathias Blank, Reinhold Kerb, Jörg Lippert, Jan‐Frederik Schlender, Matthias Schwab, Lars Kuepfer
Published 2021-07-01

Evaluation of clinical risk factors to predict high on-treatment platelet reactivity and outcome in patients with stable coronary artery disease (PREDICT-STABLE).

by Michal Droppa, Dimitri Tschernow, Karin A L Müller, Elli Tavlaki, Athanasios Karathanos, Fabian Stimpfle, Elke Schaeffeler, Matthias Schwab, Alexander Tolios, Jolanta M Siller-Matula, Meinrad Gawaz, Tobias Geisler
Published 2015-01-01

Improved Prediction of Endoxifen Metabolism by CYP2D6 Genotype in Breast Cancer Patients Treated with Tamoxifen

by Werner Schroth, Werner Schroth, Stefan Winter, Stefan Winter, Thomas Mürdter, Thomas Mürdter, Elke Schaeffeler, Elke Schaeffeler, Diana Eccles, Bryony Eccles, Balram Chowbay, Balram Chowbay, Balram Chowbay, Chiea C. Khor, Chiea C. Khor, Chiea C. Khor, Arafat Tfayli, Nathalie K. Zgheib, Michel Eichelbaum, Michel Eichelbaum, Michel Eichelbaum, Matthias Schwab, Matthias Schwab, Matthias Schwab, Matthias Schwab, Hiltrud Brauch, Hiltrud Brauch, Hiltrud Brauch
Published 2017-08-01

Association of a functional variant in the Wnt co-receptor LRP6 with early onset ileal Crohn's disease.

by Maureen J Koslowski, Zora Teltschik, Julia Beisner, Elke Schaeffeler, Guoxing Wang, Irmgard Kübler, Michael Gersemann, Rachel Cooney, Derek Jewell, Walter Reinisch, Séverine Vermeire, Paul Rutgeerts, Matthias Schwab, Eduard F Stange, Jan Wehkamp
Published 2012-01-01

Translational learning from clinical studies predicts drug pharmacokinetics across patient populations

by Markus Krauss, Ute Hofmann, Clemens Schafmayer, Svitlana Igel, Jan Schlender, Christian Mueller, Mario Brosch, Witigo von Schoenfels, Wiebke Erhart, Andreas Schuppert, Michael Block, Elke Schaeffeler, Gabriele Boehmer, Linus Goerlitz, Jan Hoecker, Joerg Lippert, Reinhold Kerb, Jochen Hampe, Lars Kuepfer, Matthias Schwab
Published 2017-03-01