Structure-function analysis of the Anopheles gambiae LRIM1/APL1C complex and its interaction with complement C3-like protein TEP1.

Malaria threatens half the world's population and exacts a devastating human toll. The principal malaria vector in Africa, the mosquito Anopheles gambiae, encodes 24 members of a recently identified family of leucine-rich repeat proteins named LRIMs. Two members of this family, LRIM1 and APL1C,...

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Bibliographic Details
Main Authors: Michael Povelones, Leanna M Upton, Katarzyna A Sala, George K Christophides
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21533217/pdf/?tool=EBI