Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition

Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition

Abstract The etiology of Parkinson’s disease is largely unknown. Genome-wide transcriptomic studies in bulk brain tissue have identified several molecular signatures associated with the disease. While these studies have the potential to shed light into the pathogenesis of Parkinson’s disease, they a...

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Bibliographic Details
Main Authors: Gonzalo S. Nido, Fiona Dick, Lilah Toker, Kjell Petersen, Guido Alves, Ole-Bjørn Tysnes, Inge Jonassen, Kristoffer Haugarvoll, Charalampos Tzoulis
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Acta Neuropathologica Communications
Subjects:
RNA sequencing
Neurodegeneration
Parkinsonism
Mitochondria
Gene expression
Online Access:http://link.springer.com/article/10.1186/s40478-020-00932-7

Internet

http://link.springer.com/article/10.1186/s40478-020-00932-7

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