Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens.

Retroviral insertional mutagenesis screens, which identify genes involved in tumor development in mice, have yielded a substantial number of retroviral integration sites, and this number is expected to grow substantially due to the introduction of high-throughput screening techniques. The data of va...

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Bibliographic Details
Main Authors: Jeroen de Ridder, Anthony Uren, Jaap Kool, Marcel Reinders, Lodewyk Wessels
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1676030?pdf=render