Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.

DNA methylation plays an important role in development and disease. The primary sites of DNA methylation in vertebrates are cytosines in the CpG dinucleotide context, which account for roughly three quarters of the total DNA methylation content in human and mouse cells. While the genomic distributio...

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Bibliographic Details
Main Authors: Michael J Ziller, Fabian Müller, Jing Liao, Yingying Zhang, Hongcang Gu, Christoph Bock, Patrick Boyle, Charles B Epstein, Bradley E Bernstein, Thomas Lengauer, Andreas Gnirke, Alexander Meissner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3234221?pdf=render