GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity

GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity

Intravascular processing of triglyceride-rich lipoproteins (TRLs) is crucial for delivery of dietary lipids fueling energy metabolism in heart and skeletal muscle and for storage in white adipose tissue. During the last decade, mechanisms underlying focal lipolytic processing of TRLs along the lumin...

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Bibliographic Details
Main Authors: Kristian Kølby Kristensen, Katrine Zinck Leth-Espensen, Anni Kumari, Anne Louise Grønnemose, Anne-Marie Lund-Winther, Stephen G. Young, Michael Ploug
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
GPIHBP1
lipoprotein lipase
intravascular lipolysis
intrinsic disorder
ANGPTL4
LU domain
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.702508/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.702508/full

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