A high throughput screen for next-generation leads targeting malaria parasite transmission
Sexual forms of malaria parasites are responsible for transmission to the mosquito. Anti-malarial drug resistance remains a serious problem and requires advent of new drug therapies. Here, the authors present a high-throughput screen of potential antimalarial compounds, identifying seventeen drug-li...
Main Authors: | Michael J. Delves, Celia Miguel-Blanco, Holly Matthews, Irene Molina, Andrea Ruecker, Sabrina Yahiya, Ursula Straschil, Matthew Abraham, María Luisa León, Oliver J. Fischer, Ainoa Rueda-Zubiaurre, Jochen R. Brandt, Álvaro Cortés, Anna Barnard, Matthew J. Fuchter, Félix Calderón, Elizabeth A. Winzeler, Robert E. Sinden, Esperanza Herreros, Francisco J. Gamo, Jake Baum |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05777-2 |
Similar Items
-
A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies
by: Sinden Robert E, et al.
Published: (2010-01-01) -
Fueling Open Innovation for Malaria Transmission-Blocking Drugs: Hundreds of Molecules Targeting Early Parasite Mosquito Stages
by: Michael Delves, et al.
Published: (2019-09-01) -
An inexpensive open source 3D-printed membrane feeder for human malaria transmission studies
by: Kathrin Witmer, et al.
Published: (2018-08-01) -
Synthetic studies on porphyrazines : biological applications and new preparative methods
by: Fuchter, Matthew John
Published: (2006) -
Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen
by: Celia Miguel-Blanco, et al.
Published: (2017-05-01)