Developing transmission-blocking strategies for malaria control.

by Robert E Sinden
Published 2017-07-01

A Plasmodium falciparum strain expressing GFP throughout the parasite's life-cycle.

by Arthur M Talman, Andrew M Blagborough, Robert E Sinden
Published 2010-02-01

Editorial: Get Over the Gut: Apicomplexan Parasite Interaction, Survival and Stage Progression in Vertebrate and Invertebrate Digestive Tracts

by Nicholas C. Smith, Nicholas C. Smith, Robert E. Sinden, Chandra Ramakrishnan
Published 2021-04-01

Female inheritance of malarial lap genes is essential for mosquito transmission.

by J Dale Raine, Andrea Ecker, Jacqui Mendoza, Rita Tewari, Rebecca R Stanway, Robert E Sinden
Published 2007-03-01

Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development.

by Shigeto Yoshida, Yohei Shimada, Daisuke Kondoh, Yoshiaki Kouzuma, Anil K Ghosh, Marcelo Jacobs-Lorena, Robert E Sinden
Published 2007-12-01

The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites.

by Michael Delves, David Plouffe, Christian Scheurer, Stephan Meister, Sergio Wittlin, Elizabeth A Winzeler, Robert E Sinden, Didier Leroy
Published 2012-02-01

A viral vectored prime-boost immunization regime targeting the malaria Pfs25 antigen induces transmission-blocking activity.

by Anna L Goodman, Andrew M Blagborough, Sumi Biswas, Yimin Wu, Adrian V Hill, Robert E Sinden, Simon J Draper
Published 2011-01-01

Wolbachia stimulates immune gene expression and inhibits plasmodium development in Anopheles gambiae.

by Zakaria Kambris, Andrew M Blagborough, Sofia B Pinto, Marcus S C Blagrove, H Charles J Godfray, Robert E Sinden, Steven P Sinkins
Published 2010-10-01

Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector.

by Ellen S C Bushell, Andrea Ecker, Timm Schlegelmilch, David Goulding, Gordon Dougan, Robert E Sinden, George K Christophides, Fotis C Kafatos, Dina Vlachou
Published 2009-08-01

Progression of Plasmodium berghei through Anopheles stephensi is density-dependent.

by Robert E Sinden, Emma J Dawes, Yasmene Alavi, Joanna Waldock, Olivia Finney, Jacqui Mendoza, Geoff A Butcher, Laura Andrews, Adrian V Hill, Sarah C Gilbert, María-Gloria Basáñez
Published 2007-12-01

Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points

by Maria L. Vainieri, Andrew M. Blagborough, Adam L. MacLean, Myriam L. R. Haltalli, Nicola Ruivo, Helen A. Fletcher, Michael P. H. Stumpf, Robert E. Sinden, Cristina Lo Celso
Published 2016-01-01

The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes.

by Ursula Straschil, Arthur M Talman, David J P Ferguson, Karen A Bunting, Zhengyao Xu, Elizabeth Bailes, Robert E Sinden, Anthony A Holder, Elizabeth F Smith, Juliet C Coates, Rita Tewari
Published 2010-09-01

Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts.

by Thomas S Churcher, Robert E Sinden, Nick J Edwards, Ian D Poulton, Thomas W Rampling, Patrick M Brock, Jamie T Griffin, Leanna M Upton, Sara E Zakutansky, Katarzyna A Sala, Fiona Angrisano, Adrian V S Hill, Andrew M Blagborough
Published 2017-01-01

Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen

by Celia Miguel-Blanco, Irene Molina, Ana I. Bardera, Beatriz Díaz, Laura de las Heras, Sonia Lozano, Carolina González, Janneth Rodrigues, Michael J. Delves, Andrea Ruecker, Gonzalo Colmenarejo, Sara Viera, María S. Martínez-Martínez, Esther Fernández, Jake Baum, Robert E. Sinden, Esperanza Herreros
Published 2017-05-01

A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion.

by David S Guttery, Benoit Poulin, David J P Ferguson, Balázs Szöőr, Bill Wickstead, Paula L Carroll, Chandra Ramakrishnan, Declan Brady, Eva-Maria Patzewitz, Ursula Straschil, Lev Solyakov, Judith L Green, Robert E Sinden, Andrew B Tobin, Anthony A Holder, Rita Tewari
Published 2012-09-01

Polyamidoamine Nanoparticles for the Oral Administration of Antimalarial Drugs

by Elisabet Martí Coma-Cros, Arnau Biosca, Joana Marques, Laura Carol, Patricia Urbán, Diana Berenguer, Maria Cristina Riera, Michael Delves, Robert E. Sinden, Juan José Valle-Delgado, Lefteris Spanos, Inga Siden-Kiamos, Paula Pérez, Krijn Paaijmans, Matthias Rottmann, Amedea Manfredi, Paolo Ferruti, Elisabetta Ranucci, Xavier Fernàndez-Busquets
Published 2018-11-01

A high throughput screen for next-generation leads targeting malaria parasite transmission

by Michael J. Delves, Celia Miguel-Blanco, Holly Matthews, Irene Molina, Andrea Ruecker, Sabrina Yahiya, Ursula Straschil, Matthew Abraham, María Luisa León, Oliver J. Fischer, Ainoa Rueda-Zubiaurre, Jochen R. Brandt, Álvaro Cortés, Anna Barnard, Matthew J. Fuchter, Félix Calderón, Elizabeth A. Winzeler, Robert E. Sinden, Esperanza Herreros, Francisco J. Gamo, Jake Baum
Published 2018-09-01

Spatial localisation of actin filaments across developmental stages of the malaria parasite.

by Fiona Angrisano, David T Riglar, Angelika Sturm, Jennifer C Volz, Michael J Delves, Elizabeth S Zuccala, Lynne Turnbull, Chaitali Dekiwadia, Maya A Olshina, Danushka S Marapana, Wilson Wong, Vanessa Mollard, Clare H Bradin, Christopher J Tonkin, Peter W Gunning, Stuart A Ralph, Cynthia B Whitchurch, Robert E Sinden, Alan F Cowman, Geoffrey I McFadden, Jake Baum
Published 2012-01-01

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

by Paul M. O’Neill, Richard K. Amewu, Susan A. Charman, Sunil Sabbani, Nina F. Gnädig, Judith Straimer, David A. Fidock, Emma R. Shore, Natalie L. Roberts, Michael H.-L. Wong, W. David Hong, Chandrakala Pidathala, Chris Riley, Ben Murphy, Ghaith Aljayyoussi, Francisco Javier Gamo, Laura Sanz, Janneth Rodrigues, Carolina Gonzalez Cortes, Esperanza Herreros, Iñigo Angulo-Barturén, María Belén Jiménez-Díaz, Santiago Ferrer Bazaga, María Santos Martínez-Martínez, Brice Campo, Raman Sharma, Eileen Ryan, David M. Shackleford, Simon Campbell, Dennis A. Smith, Grennady Wirjanata, Rintis Noviyanti, Ric N. Price, Jutta Marfurt, Michael J. Palmer, Ian M. Copple, Amy E. Mercer, Andrea Ruecker, Michael J. Delves, Robert E. Sinden, Peter Siegl, Jill Davies, Rosemary Rochford, Clemens H. M. Kocken, Anne-Marie Zeeman, Gemma L. Nixon, Giancarlo A. Biagini, Stephen A. Ward
Published 2017-05-01