The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations.

The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations.

A previous study suggested an association of the single nucleotide polymorphism (SNP) rs72796353 (IVS4+10 A>C) in the NOD2 gene with susceptibility to Crohn's disease (CD). However, this finding has not been confirmed. Given that NOD2 variants still represent the most important predictors fo...

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Bibliographic Details
Main Authors: Fabian Schnitzler, Matthias Friedrich, Christiane Wolf, Johannes Stallhofer, Marianne Angelberger, Julia Diegelmann, Torsten Olszak, Cornelia Tillack, Florian Beigel, Burkhard Göke, Jürgen Glas, Peter Lohse, Stephan Brand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4493062?pdf=render

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http://europepmc.org/articles/PMC4493062?pdf=render

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