Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF.

Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF.

Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus that causes an aggressive T-cell malignancy and a variety of inflammatory conditions. The integrated provirus includes a single binding site for the epigenomic insulator, CCCTC-binding protein (CTCF), but its function remains unclear. In th...

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Bibliographic Details
Main Authors: Xiaogang Cheng, Ancy Joseph, Victor Castro, Alice Chen-Liaw, Zachary Skidmore, Takaharu Ueno, Jun-Ichi Fujisawa, Daniel A Rauch, Grant A Challen, Michael P Martinez, Patrick Green, Malachi Griffith, Jacqueline E Payton, John R Edwards, Lee Ratner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009577

Internet

https://doi.org/10.1371/journal.ppat.1009577

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