Cation Involvement in Telomestatin Binding to G-Quadruplex DNA

The binding mode of telomestatin to G-quadruplex DNA has been investigated using electrospray mass spectrometry, by detecting the intact complexes formed in ammonium acetate. The mass measurements show the incorporation of one extra ammonium ion in the telomestatin complexes. Experiments on telomest...

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Bibliographic Details
Main Authors: Frédéric Rosu, Valérie Gabelica, Nicolas Smargiasso, Gabriel Mazzucchelli, Kazuo Shin-Ya, Edwin De Pauw
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2010/121259