Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Reduces Melanoma Metastasis in Liver

Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Reduces Melanoma Metastasis in Liver

High circulating cholesterol is associated with hypercholesterolemia, atherosclerosis, and stroke. However, the relation between cholesterol and tumorigenesis/metastasis is controversial. The proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates low-density lipoprotein cholesterol homeost...

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Bibliographic Details
Main Authors: Xiaowei Sun, Rachid Essalmani, Robert Day, Abdel M. Khatib, Nabil G. Seidah, Annik Prat
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800492

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http://www.sciencedirect.com/science/article/pii/S1476558612800492

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