Evaluation of 41 candidate gene variants for obesity in the EPIC-Potsdam cohort by multi-locus stepwise regression.

OBJECTIVE: Obesity has become a leading preventable cause of morbidity and mortality in many parts of the world. It is thought to originate from multiple genetic and environmental determinants. The aim of the current study was to introduce haplotype-based multi-locus stepwise regression (MSR) as a m...

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Bibliographic Details
Main Authors: Sven Knüppel, Klaus Rohde, Karina Meidtner, Dagmar Drogan, Hermann-Georg Holzhütter, Heiner Boeing, Eva Fisher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3709896?pdf=render