Clinical Clostridium difficile: clonality and pathogenicity locus diversity.

Clostridium difficile infection (CDI) is an important cause of mortality and morbidity in healthcare settings. The major virulence determinants are large clostridial toxins, toxin A (tcdA) and toxin B (tcdB), encoded within the pathogenicity locus (PaLoc). Isolates vary in pathogenicity from hypervi...

Full description

Bibliographic Details
Main Authors: Kate E Dingle, David Griffiths, Xavier Didelot, Jessica Evans, Alison Vaughan, Melina Kachrimanidou, Nicole Stoesser, Keith A Jolley, Tanya Golubchik, Rosalind M Harding, Tim E Peto, Warren Fawley, A Sarah Walker, Mark Wilcox, Derrick W Crook
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625511/?tool=EBI