Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells.

Embelin, a natural quinone found in the fruits of Embelia ribes, is commonly used in Ayurvedic home medicine for a variety of therapeutic potentials including anti-inflammation, anti-fever, anti-bacteria and anti-cancer. Molecular mechanisms of these activities and cellular targets have not been cla...

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Bibliographic Details
Main Authors: Nupur Nigam, Abhinav Grover, Sukriti Goyal, Shashank P Katiyar, Priyanshu Bhargava, Pi-Chao Wang, Durai Sundar, Sunil C Kaul, Renu Wadhwa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4574062?pdf=render