miRNA Modulation and Antitumor Activity by the Extra-Virgin Olive Oil Polyphenol Oleacein in Human Melanoma Cells

miRNA Modulation and Antitumor Activity by the Extra-Virgin Olive Oil Polyphenol Oleacein in Human Melanoma Cells

Extra-virgin olive oil (EVOO) polyphenols contribute to Mediterranean diet health-promoting properties. One of the most abundant secoiridoid present in EVOO, Oleacein (OA), demonstrated anticancer activity against several tumors. Nevertheless, its role against melanoma has not still investigated. Th...

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Bibliographic Details
Main Authors: Sara Carpi, Beatrice Polini, Clementina Manera, Maria Digiacomo, Jasmine Esposito Salsano, Marco Macchia, Egeria Scoditti, Paola Nieri
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
melanoma
oleacein
extra-virgin olive oil
microRNA
mTOR
BCL2
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.574317/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.574317/full

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