Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges

Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges

Abstract We previously developed a temperature-sensitive, and NS1 gene deleted live attenuated influenza vaccine (DelNS1-LAIV) and demonstrated its potent protective efficacy in intranasally vaccinated mice. Here we investigated whether intradermal (i.d.) vaccination induces protective immunity. Our...

Full description

Bibliographic Details
Main Authors: Andrew Chak-Yiu Lee, Anna Jinxia Zhang, Can Li, Yanxia Chen, Feifei Liu, Yan Zhao, Hin Chu, Carol Ho-Yan Fong, Pui Wang, Siu-Ying Lau, Kelvin Kai-Wang To, Honglin Chen, Kwok-Yung Yuen
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00359-8

Internet

https://doi.org/10.1038/s41541-021-00359-8

Similar Items