Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice

Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice

The nuclear hormone receptor constitutive androstane receptor (CAR, NR1I3) regulates detoxification of xenobiotics and endogenous molecules, and has been shown to be involved in the metabolism of hepatic bile acids and cholesterol. The goal of this study was to address potential effects of CAR on th...

Full description

Bibliographic Details
Main Authors: David Masson, Mohamed Qatanani, Anne Laure Sberna, Rui Xiao, Jean Paul Pais de Barros, Jacques Grober, Valerie Deckert, Anne Athias, Philippe Gambert, Laurent Lagrost, David D. Moore, Mahfoud Assem
Format: Article
Language:English
Published: Elsevier 2008-08-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein A-I
bile acids
cholesterol
1,4-bis[2-(3,5-dichloropyridyloxy)]benzene
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520346861

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520346861

Similar Items