Use of Specific Chemical Reagents for Detection of Modified Nucleotides in RNA

Naturally occurring cellular RNAs contain an impressive number of chemically distinct modified residues which appear posttranscriptionally, as a result of specific action of the corresponding RNA modification enzymes. Over 100 different chemical modifications have been identified and characterized u...

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Bibliographic Details
Main Authors: Isabelle Behm-Ansmant, Mark Helm, Yuri Motorin
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2011/408053