The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon

The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon

Tumour metastasis accounts for over 90% of cancer related deaths. The platelet is a key blood component, which facilitates efficient metastasis. This study aimed to understand the molecular mechanisms involved in tumour-platelet cell interactions.The interaction between cancer cells and platelets wa...

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Bibliographic Details
Main Authors: Cathy D. Spillane, Niamh M. Cooke, Mark P. Ward, Dermot Kenny, Gordon Blackshields, Tanya Kelly, Mark Bates, Yanmei Huang, Cara Martin, Sinead Skehan, Aoife Canney, Michael Gallagher, Paul Smyth, Nathan Brady, Andres Clarke, Bashir Mohamed, Lucy Norris, Doug A. Brooks, Robert D. Brooks, Jessica K. Heatlie, Stavros Selemidis, Sean Hanniffy, Eric Dixon, Orla Sheils, Sharon A. O'Toole, John J. O'Leary
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Translational Oncology
Subjects:
Cancer
Platelets
Metastasis
5-gene panel
PAI-1
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321002217

Internet

http://www.sciencedirect.com/science/article/pii/S1936523321002217

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