Unique transcriptomic response to sepsis is observed among patients of different age groups.

Unique transcriptomic response to sepsis is observed among patients of different age groups.

Sepsis is a major cause of morbidity and mortality, especially at the extremes of age. To understand the human age-specific transcriptomic response to sepsis, a multi-cohort, pooled analysis was conducted on adults, children, infants, and neonates with and without sepsis. Nine public whole-blood gen...

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Bibliographic Details
Main Authors: Steven L Raymond, María Cecilia López, Henry V Baker, Shawn D Larson, Philip A Efron, Timothy E Sweeney, Purvesh Khatri, Lyle L Moldawer, James L Wynn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5590890?pdf=render

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http://europepmc.org/articles/PMC5590890?pdf=render

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