Strategy for Development of Site-Specific Ubiquitin Antibodies

Strategy for Development of Site-Specific Ubiquitin Antibodies

Protein ubiquitination is a key post-translational modification regulating a wide range of biological processes. Ubiquitination involves the covalent attachment of the small protein ubiquitin to a lysine of a protein substrate. In addition to its well-established role in protein degradation, protein...

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Bibliographic Details
Main Authors: Ila van Kruijsbergen, Monique P. C. Mulder, Michael Uckelmann, Tibor van Welsem, John de Widt, Aldo Spanjaard, Heinz Jacobs, Farid El Oualid, Huib Ovaa, Fred van Leeuwen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Chemistry
Subjects:
ubiquitin
histone H2B
H2B-K123ub
PCNA
monoclonal antibody
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00111/full

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https://www.frontiersin.org/article/10.3389/fchem.2020.00111/full

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