Significant Prognostic Features and Patterns of Somatic Mutations in Human Cancers

TP53 is the most frequently altered gene in human cancers. Numerous retrospective studies have related its mutation and abnormal p53 protein expression to poor patient survival. Nonetheless, the clinical significance of TP53 ( p53 ) status has been a controversial issue. In this work, we aimed to ch...

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Bibliographic Details
Main Authors: Wensheng Zhang, Andrea Edwards, Erik K Flemington, Kun Zhang
Format: Article
Language:English
Published: SAGE Publishing 2017-02-01
Series:Cancer Informatics
Online Access:https://doi.org/10.1177/1176935117691267