Glial promoter selectivity following AAV-delivery to the immature brain.

Glial promoter selectivity following AAV-delivery to the immature brain.

Recombinant adeno-associated virus (AAV) vectors are versatile tools for gene transfer to the central nervous system (CNS) and proof-of-concept studies in adult rodents have shown that the use of cell type-specific promoters is sufficient to target AAV-mediated transgene expression to glia. However,...

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Bibliographic Details
Main Authors: Georg von Jonquieres, Nadine Mersmann, Claudia Bettina Klugmann, Anne Editha Harasta, Beat Lutz, Orla Teahan, Gary David Housley, Dominik Fröhlich, Eva-Maria Krämer-Albers, Matthias Klugmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23799030/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23799030/?tool=EBI

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