A functional insulator screen identifies NURF and dREAM components to be required for enhancer-blocking.

A functional insulator screen identifies NURF and dREAM components to be required for enhancer-blocking.

Chromatin insulators of higher eukaryotes functionally divide the genome into active and inactive domains. Furthermore, insulators regulate enhancer/promoter communication, which is evident from the Drosophila bithorax locus in which a multitude of regulatory elements control segment specific gene a...

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Bibliographic Details
Main Authors: Dorte Bohla, Martin Herold, Imke Panzer, Melanie K Buxa, Tamer Ali, Jeroen Demmers, Marcus Krüger, Maren Scharfe, Michael Jarek, Marek Bartkuhn, Rainer Renkawitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4172637?pdf=render

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http://europepmc.org/articles/PMC4172637?pdf=render

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