NCoR1: Putting the Brakes on the Dendritic Cell Immune Tolerance

NCoR1: Putting the Brakes on the Dendritic Cell Immune Tolerance

Summary: Understanding the mechanisms fine-tuning immunogenic versus tolerogenic balance in dendritic cells (DCs) is of high importance for therapeutic approaches. We found that NCoR1-mediated direct repression of the tolerogenic program in conventional DCs is essential for induction of an optimal i...

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Bibliographic Details
Main Authors: Abdul Ahad, Mathias Stevanin, Shuchi Smita, Gyan Prakash Mishra, Dheerendra Gupta, Sebastian Waszak, Uday Aditya Sarkar, Soumen Basak, Bhawna Gupta, Hans Acha-Orbea, Sunil Kumar Raghav
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219303025

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http://www.sciencedirect.com/science/article/pii/S2589004219303025

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