Pleiotropic and sex-specific effects of cancer GWAS SNPs on melanoma risk in the population architecture using genomics and epidemiology (PAGE) study.

Pleiotropic and sex-specific effects of cancer GWAS SNPs on melanoma risk in the population architecture using genomics and epidemiology (PAGE) study.

Several regions of the genome show pleiotropic associations with multiple cancers. We sought to evaluate whether 181 single-nucleotide polymorphisms previously associated with various cancers in genome-wide association studies were also associated with melanoma risk.We evaluated 2,131 melanoma cases...

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Bibliographic Details
Main Authors: Jonathan M Kocarnik, S Lani Park, Jiali Han, Logan Dumitrescu, Iona Cheng, Lynne R Wilkens, Fredrick R Schumacher, Laurence Kolonel, Chris S Carlson, Dana C Crawford, Robert J Goodloe, Holli H Dilks, Paxton Baker, Danielle Richardson, Tara C Matise, José Luis Ambite, Fengju Song, Abrar A Qureshi, Mingfeng Zhang, David Duggan, Carolyn Hutter, Lucia Hindorff, William S Bush, Charles Kooperberg, Loic Le Marchand, Ulrike Peters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4366224?pdf=render

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http://europepmc.org/articles/PMC4366224?pdf=render

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