Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics
The definition of regulatory landscape at chronic lymphocytic leukaemia (CLL) risk loci is limited. Here, the authors perform an epigenomic characterisation of 42 known risk loci in CLL and normal B cells at different developmental stages and show active chromatin and target genes in the risk loci.
Main Authors: | , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-11582-2 |