FOXO3 on the Road to Longevity: Lessons From SNPs and Chromatin Hubs

Health span is driven by a precise interplay between genes and the environment. Cell response to environmental cues is mediated by signaling cascades and genetic variants that affect gene expression by regulating chromatin plasticity. Indeed, they can promote the interaction of promoters with regula...

Full description

Bibliographic Details
Main Authors: Paola Sanese, Giovanna Forte, Vittoria Disciglio, Valentina Grossi, Cristiano Simone
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037019301011