Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers.

BACKGROUND:High-grade serous ovarian and endometrial cancers are the most lethal female reproductive tract malignancies worldwide. In part, failure to treat these two aggressive cancers successfully centers on the fact that while the majority of patients are diagnosed based on current surveillance s...

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Main Authors: Elena Pereira, Olga Camacho-Vanegas, Sanya Anand, Robert Sebra, Sandra Catalina Camacho, Leopold Garnar-Wortzel, Navya Nair, Erin Moshier, Melissa Wooten, Andrew Uzilov, Rong Chen, Monica Prasad-Hayes, Konstantin Zakashansky, Ann Marie Beddoe, Eric Schadt, Peter Dottino, John A Martignetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4696808?pdf=render