Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer

Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer

Simultaneous targeting of the prostate-specific membrane antigen (PSMA) and gastrin-releasing peptide receptor (GRPR) could improve the diagnostic accuracy in prostate cancer (PCa). The aim of this study was to develop a PSMA/GRPR-targeting bispecific heterodimer for SPECT and positron emission tomo...

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Bibliographic Details
Main Authors: Bogdan Mitran, Zohreh Varasteh, Ayman Abouzayed, Sara S. Rinne, Emmi Puuvuori, Maria De Rosa, Mats Larhed, Vladimir Tolmachev, Anna Orlova, Ulrika Rosenström
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
PSMA
GRPR
heterodimer
molecular imaging
prostate cancer
PET
SPECT
Online Access:https://www.mdpi.com/2072-6694/11/9/1371

Internet

https://www.mdpi.com/2072-6694/11/9/1371

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