Establishment of a Plasmid-Based Reverse Genetics System for the Cell Culture-Adapted Hepatitis E Virus Genotype 3c Strain 47832c

Establishment of a Plasmid-Based Reverse Genetics System for the Cell Culture-Adapted Hepatitis E Virus Genotype 3c Strain 47832c

The hepatitis E virus (HEV) causes acute and chronic hepatitis in humans. Investigation of HEV replication is hampered by the lack of broadly applicable, efficient cell culture systems and tools for site-directed mutagenesis of HEV. The cell culture-adapted genotype 3c strain 47832c, which represent...

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Bibliographic Details
Main Authors: Johannes Scholz, Christine Bächlein, Ashish K. Gadicherla, Alexander Falkenhagen, Simon H. Tausch, Reimar Johne
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pathogens
Subjects:
hepatitis e virus
genotype 3c
cell culture
reverse genetics system
site-directed mutagenesis
Online Access:https://www.mdpi.com/2076-0817/9/3/157

Internet

https://www.mdpi.com/2076-0817/9/3/157

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