Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment
M2-like tumor-associated macrophages (TAMs) in the tumor tissues promote tumor progression by various mechanisms and represent possible targets of antitumor therapy. In the present study, we tested whether compounds from Epimedii Herba inhibit macrophage polarization to the M2/protumorigenic phenoty...
Main Authors: | Cheng Pan, Yukio Fujiwara, Hasita Horlad, Daisuke Shiraishi, Toyohisa Iriki, Jyunko Tsuboki, Tsuyoshi Ikeda, Yoshihiro Komohara |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-03-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2020.00262/full |
Similar Items
-
The Anticancer Properties of Herba Epimedii and Its Main Bioactive Componentsicariin and Icariside II
by: Meixia Chen, et al.
Published: (2016-09-01) -
The Effects of Epimedii Herba on a Hypothyroidism Rat Model induced by PTU(6-Propyl, 2-thiouracil)
by: Min Jin Hong, et al.
Published: (2011-12-01) -
Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications
by: Ho Pan Cheung, et al.
Published: (2010-11-01) -
Optimization of the process for purifying icariin from Herba Epimedii by macroporous resin and the regulatory role of icariin in the tumor immune microenvironment
by: Xin Zheng, et al.
Published: (2019-10-01) -
Effects of the combined extracts of Herba Epimedii and Fructus Ligustrilucidi on airway remodeling in the asthmatic rats with the treatment of budesonide
by: Xiufeng Tang, et al.
Published: (2017-08-01)