Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL.

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL.

Elevated plasma concentration of the pro-atherogenic oxidized low density lipoprotein cholesterol (LDL) triggers adverse effects in pancreatic beta-cells and is associated with type 2 diabetes. Here, we investigated whether the endoplasmic reticulum (ER) stress is a key player coupling oxidative str...

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Bibliographic Details
Main Authors: Valérie Plaisance, Saška Brajkovic, Mathie Tenenbaum, Dimitri Favre, Hélène Ezanno, Amélie Bonnefond, Caroline Bonner, Valéry Gmyr, Julie Kerr-Conte, Benoit R Gauthier, Christian Widmann, Gérard Waeber, François Pattou, Philippe Froguel, Amar Abderrahmani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5026355?pdf=render

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http://europepmc.org/articles/PMC5026355?pdf=render

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