Therapeutic Potential for Regulation of the Nuclear Factor Kappa-B Transcription Factor p65 to Prevent Cellular Senescence and Activation of Pro-Inflammatory in Mesenchymal Stem Cells

Therapeutic Potential for Regulation of the Nuclear Factor Kappa-B Transcription Factor p65 to Prevent Cellular Senescence and Activation of Pro-Inflammatory in Mesenchymal Stem Cells

Mesenchymal stem cells have an important potential in the treatment of age-related diseases. In the last years, small extracellular vesicles derived from these stem cells have been proposed as cell-free therapies. Cellular senescence and proinflammatory activation are involved in the loss of therape...

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Bibliographic Details
Main Authors: Rocío Mato-Basalo, Miriam Morente-López, Onno J Arntz, Fons A. J. van de Loo, Juan Fafián-Labora, María C. Arufe
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
mesenchymal stem cells
inflamm-aging
cellular senescence
SASP
sEV
Online Access:https://www.mdpi.com/1422-0067/22/7/3367

Internet

https://www.mdpi.com/1422-0067/22/7/3367

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