The complex domain architecture of SAMD9 family proteins, predicted STAND-like NTPases, suggests new links to inflammation and apoptosis

Abstract We report a comprehensive computational dissection of the domain architecture of the SAMD9 family proteins that are involved in antivirus and antitumor response in humans. We show that the SAMD9 protein family is represented in most animals and also, unexpectedly, in bacteria, in particular...

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Bibliographic Details
Main Authors: Sergei L. Mekhedov, Kira S. Makarova, Eugene V. Koonin
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Biology Direct
Online Access:http://link.springer.com/article/10.1186/s13062-017-0185-2