Identification of 34 novel proinflammatory proteins in a genome-wide macrophage functional screen.

Signal transduction pathways activated by Toll-like Receptors and the IL-1 family of cytokines are fundamental to mounting an innate immune response and thus to clearing pathogens and promoting wound healing. Whilst mechanistic understanding of the regulation of innate signalling pathways has advanc...

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Bibliographic Details
Main Authors: David H Wyllie, Karen C Søgaard, Karen Holland, Xu Yaobo, Migena Bregu, Adrian V S Hill, Endre Kiss-Toth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3409161?pdf=render