Elucidating the Consequences of Heparan Sulfate Binding by Heparanase 2

Unlike the intense research effort devoted to exploring the significance of heparanase in human diseases, very little attention was given to its close homolog, heparanase 2 (Hpa2). The emerging role of Hpa2 in a rare autosomal recessive congenital disease called urofacial syndrome (UFS), clearly ind...

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Bibliographic Details
Main Authors: Miriam Gross-Cohen, Sari Feld, Gil Arvatz, Neta Ilan, Israel Vlodavsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.627463/full