Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study.

Osteoporosis, the most prevalent metabolic bone disease among older people, increases risk for low trauma hip fractures (HF) that are associated with high morbidity and mortality. Hip bone size (BS) has been identified as one of the key measurable risk factors for HF. Although hip BS is highly genet...

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Main Authors: Yao-Zhong Liu, Scott G Wilson, Liang Wang, Xiao-Gang Liu, Yan-Fang Guo, Jian Li, Han Yan, Panos Deloukas, Nicole Soranzo, Usha Chinappen-Horsley, Alessandra Cervino, Frances M Williams, Dong-Hai Xiong, Yin-Ping Zhang, Tian-Bo Jin, Shawn Levy, Christopher J Papasian, Betty M Drees, James J Hamilton, Robert R Recker, Tim D Spector, Hong-Wen Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2522269?pdf=render