CFTR dysregulation drives active selection of the gut microbiome.

CFTR dysregulation drives active selection of the gut microbiome.

Patients with cystic fibrosis (CF) have altered fecal microbiomes compared to those of healthy controls. The magnitude of this dysbiosis correlates with measures of CF gastrointestinal (GI) disease, including GI inflammation and nutrient malabsorption. However, whether this dysbiosis is caused by mu...

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Bibliographic Details
Main Authors: Stacey M Meeker, Kevin S Mears, Naseer Sangwan, Mitchell J Brittnacher, Eli J Weiss, Piper M Treuting, Nicholas Tolley, Christopher E Pope, Kyle R Hager, Anh T Vo, Jisun Paik, Charles W Frevert, Hillary S Hayden, Lucas R Hoffman, Samuel I Miller, Adeline M Hajjar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008251

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https://doi.org/10.1371/journal.ppat.1008251

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