MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

A novel human coronavirus, SARS-CoV, emerged suddenly in 2003, causing approximately 8000 human cases and more than 700 deaths worldwide. Since most animal models fail to faithfully recapitulate the clinical course of SARS-CoV in humans, the virus and host factors that mediate disease pathogenesis r...

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Bibliographic Details
Main Authors: Timothy Sheahan, Thomas E Morrison, William Funkhouser, Satoshi Uematsu, Shizou Akira, Ralph S Baric, Mark T Heise
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2587915?pdf=render

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http://europepmc.org/articles/PMC2587915?pdf=render

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