Effect of pistachio kernel extracts in MCF-7 breast cancer cells: Inhibition of cell proliferation, induction of ROS production, modulation of glycolysis and of mitochondrial respiration

Effect of pistachio kernel extracts in MCF-7 breast cancer cells: Inhibition of cell proliferation, induction of ROS production, modulation of glycolysis and of mitochondrial respiration

The effects of ground pistachio kernel extracts have been evaluated on cellular viability, intracellular reactive oxygen species (ROS) production and cell death in MCF-7 breast cancer cells. Results showed a significant decrease in cell viability in a dose and time dependent manner. 48 h-treatments...

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Bibliographic Details
Main Authors: Patricia Reboredo-Rodríguez, Carmen González-Barreiro, Beatriz Cancho-Grande, Jesús Simal-Gándara, Francesca Giampieri, Tamara Y. Forbes-Hernández, Massimiliano Gasparrini, Sadia Afrin, Danila Cianciosi, Piera P. Manna, Alfonso Varela-López, Rosa M. Ojeda-Amador, Giuseppe Fregapane, María Desamparados Salvador, Maurizio Battino
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Journal of Functional Foods
Subjects:
Pistachio kernel
Phenolic compounds
Intracellular reactive oxygen species (ROS)
Apoptosis
Energetic metabolism
Breast cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618301397

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http://www.sciencedirect.com/science/article/pii/S1756464618301397

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