Myeloid-related protein-14 contributes to protective immunity in gram-negative pneumonia derived sepsis.

Klebsiella (K.) pneumoniae is a common cause of pneumonia-derived sepsis. Myeloid related protein 8 (MRP8, S100A8) and MRP14 (S100A9) are the most abundant cytoplasmic proteins in neutrophils. They can form MRP8/14 heterodimers that are released upon cell stress stimuli. MRP8/14 reportedly exerts an...

Full description

Bibliographic Details
Main Authors: Ahmed Achouiti, Thomas Vogl, Constantin F Urban, Marc Röhm, Tijmen J Hommes, Marieke A D van Zoelen, Sandrine Florquin, Johannes Roth, Cornelis van 't Veer, Alex F de Vos, Tom van der Poll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3486918?pdf=render