Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality

Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality

Metabolic syndrome: SGLT2i prevents diabetic cachexia and prolongs survival Sodium-glucose cotransporter 2 inhibitor (SGLT2i) has a favorable effect on mortality of diabetic subjects, but the mechanism stays unclear. Taichi Sugizaki at Kumamoto University examined SGLT2i effects in severe diabetic o...

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Bibliographic Details
Main Authors: Taichi Sugizaki, Shunshun Zhu, Ge Guo, Akiko Matsumoto, Jiabin Zhao, Motoyoshi Endo, Haruki Horiguchi, Jun Morinaga, Zhe Tian, Tsuyoshi Kadomatsu, Keishi Miyata, Hiroshi Itoh, Yuichi Oike
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:npj Aging and Mechanisms of Disease
Online Access:https://doi.org/10.1038/s41514-017-0012-0

Internet

https://doi.org/10.1038/s41514-017-0012-0

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