<i>N</i>-Acetylcysteine Reduces Skeletal Muscles Oxidative Stress and Improves Grip Strength in Dysferlin-Deficient Bla/J Mice

<i>N</i>-Acetylcysteine Reduces Skeletal Muscles Oxidative Stress and Improves Grip Strength in Dysferlin-Deficient Bla/J Mice

Dysferlinopathy is an autosomal recessive muscular dystrophy resulting from mutations in the dysferlin gene. Absence of dysferlin in the sarcolemma and progressive muscle wasting are hallmarks of this disease. Signs of oxidative stress have been observed in skeletal muscles of dysferlinopathy patien...

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Bibliographic Details
Main Authors: Paz García-Campos, Ximena Báez-Matus, Carlos Jara-Gutiérrez, Marilyn Paz-Araos, César Astorga, Luis A. Cea, Viviana Rodríguez, Jorge A. Bevilacqua, Pablo Caviedes, Ana M. Cárdenas
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
dysferlin
dysferlinopathy
oxidative stress
<i>N</i>-acetylcysteine
Online Access:https://www.mdpi.com/1422-0067/21/12/4293

Internet

https://www.mdpi.com/1422-0067/21/12/4293

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