Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential

Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential

Cellular stressors can impact clonal hematopoiesis. Here, the authors explore the impact of cytotoxic therapy and hematopoietic transplantation on clonal expansion, suggesting different stressors can promote expansion of distinct long-lived clones.

Bibliographic Details
Main Authors: Terrence N. Wong, Christopher A. Miller, Matthew R. M. Jotte, Nusayba Bagegni, Jack D. Baty, Amy P. Schmidt, Amanda F. Cashen, Eric J. Duncavage, Nichole M. Helton, Mark Fiala, Robert S. Fulton, Sharon E. Heath, Megan Janke, Kierstin Luber, Peter Westervelt, Ravi Vij, John F. DiPersio, John S. Welch, Timothy A. Graubert, Matthew J. Walter, Timothy J. Ley, Daniel C. Link
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-02858-0

Internet

https://doi.org/10.1038/s41467-018-02858-0

Similar Items