The Effect of Proline <i>cis</i>-<i>trans</i> Isomerization on the Folding of the C-Terminal SH2 Domain from p85
SH2 domains are protein domains that modulate protein−protein interactions through a specific interaction with sequences containing phosphorylated tyrosines. In this work, we analyze the folding pathway of the C-terminal SH2 domain of the p85 regulatory subunit of the protein PI3K, which p...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-12-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/1/125 |