Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain

Cholesterol is implicated to play a role in Alzheimer disease pathology. Therefore, the concentrations of cholesterol, its precursors, and its degradation products in brain homogenates of aging wild-type and β-amyloid precursor protein transgenic mice carrying the Swedish mutation (APP23) were analy...

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Bibliographic Details
Main Authors: Dieter Lütjohann, Andreas Brzezinka, Esther Barth, Dorothee Abramowski, Matthias Staufenbiel, Klaus von Bergmann, Konrad Beyreuther, Gerd Multhaup, Thomas A. Bayer
Format: Article
Language:English
Published: Elsevier 2002-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752031470X