Siglec receptors impact mammalian lifespan by modulating oxidative stress

Siglec receptors impact mammalian lifespan by modulating oxidative stress

Aging is a multifactorial process that includes the lifelong accumulation of molecular damage, leading to age-related frailty, disability and disease, and eventually death. In this study, we report evidence of a significant correlation between the number of genes encoding the immunomodulatory CD33-r...

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Bibliographic Details
Main Authors: Flavio Schwarz, Oliver MT Pearce, Xiaoxia Wang, Annie N Samraj, Heinz Läubli, Javier O Garcia, Hongqiao Lin, Xiaoming Fu, Andrea Garcia-Bingman, Patrick Secrest, Casey E Romanoski, Charles Heyser, Christopher K Glass, Stanley L Hazen, Nissi Varki, Ajit Varki, Pascal Gagneux
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
inflammation
reactive oxygen species
aging
Siglec
Online Access:https://elifesciences.org/articles/06184

Internet

https://elifesciences.org/articles/06184

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