Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis
Abstract Background High throughput single-cell RNA sequencing (scRNA-Seq) has emerged as a powerful tool for exploring cellular heterogeneity among complex human cancers. scRNA-Seq studies using fresh human surgical tissue are logistically difficult, preclude histopathological triage of samples, an...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-05-01
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Series: | Genome Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13073-021-00885-z |